Top Definition
in similar fashion to genocide, it is the deliberate and systematic destruction in whole or in part, of an ethnic, racial, religious, or national group OF MICE...usually by angry homeowners who want to stop the littler fuckers from shitting all over the house and eating their food

usually killed in numbers by various types of mouse traps or rodenticides to prevent and/or stop further colonization of where the mice have set up a habitat

total domination and destuction of mice
with my d-con and victor mouse traps, the mousicide will now commence!
af mousekillah 2. januar 2010

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