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1.
Two women that are very close friends that practically seem like they are lesbians.
When I saw those two chicks hugging I said to myself, "les-bi-friends".
af suckmyduck 26. juli 2005
 
2.
two or more girls who appear to be good friends but are obviously all in the same closet.
Girl 1: Hey, lets have a slumber party!
Girl 2: Yeah and we can have give each other facials and full body massages!
Girl 3: Then, we can all go to the bathroom together!

Random bystander: Hey dude, check the lesbifriends! *high fives*
af BiancaDoesThat 29. april 2008
 
3.
this is where to girls are really good friends. Much like a bromance, accept between two girls, or women.
Nikki and Paris were lesbi-friends.
af Poopskie 17. januar 2009
 
4.
A straight girl who is friends with lesbians.
"Melissa is SJ's lesbi-friend."
af Darkluna 28. maj 2009
 
5.
A pick up line, employed by lesbian culture, directed towards hetero-sexual women.
Hey girl, lesbi-friends?
af rebreakthebone 2. maj 2011