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1.
A blanket term for higher quality marijuana.
Synonym: dank
Stoner A: Hey man, you got any drough?
Cannabis Provider: Yessir, straight drough, no seeds no stems.
Stoner A: Far out dude, I'm really getting sick of sorting through seeds.

Example 2. "Blow that drough!"
af BLOWDATDROUGH 3. december 2009
 
2.
pronounced like "drew" means anything that rhymes with you.
what are drough droughing? (what are you doing?)
af Drough 24. september 2005
 
3.
Drugs of some type, I think.
Yo, check out this drough I gots. It's the shiznit.
af Christopher B 21. juli 2006