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1.
a female pussy
clean that twot w/ a douche
af antony 14. november 2003
 
2.
'The word on the street'
Meaning a rumor or something known in the grapevine. Mostly used in the areas around Bledmeer and Benowyc.
or 'The way of the Stams'
A way to refer to gangs who pick on smaller gangs or individuals.
Sometimes used as an affirmative exclamation.

"Hey Jimmy, twots is that you're into cats"
Or
"Who said I hung around bridges all day?"
"Twots"
af Onelith 20. juni 2006
 
3.
a female who has tattoos and also have a nice pair of titties
Me and a friend was at a bar drinking our beer when this fine looking Two T's came in. She was a brunette who had tattoos on her upper arms and her breasts was popping out of her tank-top.
af Thieng 29. april 2011
 
4.
Someone who tweets a lot.
"Yeah, she's funny, but she's a super twot."
af falstar 22. juli 2012
 
5.
It's an acronym for 'total waste of time', often used on the internet, to describe things (pictures, videos, etc.) that someone wished they hadn't watched.

Refer to: RickRoll.
Well, that was a TWOT.

(Response to a message): TWOT!
af Dutty4u 4. august 2008
 
6.
Someone, who without effort, makes a right proper useless waste of space of himself. Not annoying, just a useless twot.
When he died it was a relief to us all... the useless twot.
af clemstar 27. februar 2009
 
7.
the va-j. it is the golden slit in which pleasure for women arises. the love box...or in blatent terms, the pus.
1. My roommate Kristie is such a fucking twot, she can't even spell the word.
2. Put your dick in my wet twot; you make my pus wet.
af schmundy 29. oktober 2006