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1.
Noun, Plural: Twixers.
Definition: A Twenty Six Ounce bottle of liquor, derived from the combination of Twenty (Tw), and Sixer (ixer). Commonly used in party situations
Yo man this party is gonna be ill tonight! I know eh, we should definetly pick up a couple twixers of Bacardi 151.
af MandelaC 23. december 2005
 
2.
A 26oz bottle of alcohol
Yo dogg lets go grab a twixer of CC
af Snoop 20. juli 2002