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1.
One of the best Chicano Rap Artists from the Westcoast.
He is one serio vato. Serio is one of the best chicano rappers I know. Nightmares Turned Into Reality from Califas 2 Washifas
af Jonathan Perez 27. december 2007
 
2.
spanish for serious
boy: Quiero los zapatos azules.

girl: serio?!?!?!?!?
af 662614 22. september 2009
 
3.
Means the same as "serious"
"Are you serious?" becomes "Serio?"
af Starry 8. december 2004
 
4.
For reals , Is that so. Telling me the truth. Seriously
I'm Serio, I want to go to that party tonight
af Katrina 16. november 2004
 
5.
Pronounced: Se-Ree-O, the 'se' part is elongated, said with an arched brow and tilting the head back.

Meaning(s): 'is that so'; 'are you serious'
Girl: I wanna get some hubcap spinners for my focus
Guy: Serio
Girl: =\
af SaraZ 3. maj 2005
 
6.
the state or action of complete domination of the competition.

"Jeff completely serioed the other team's defense by scoring three touchdowns"
af Edinburgh984 8. marts 2009
 
7.
internet abbreviation for the word serious, usually used in combination with "r u" or "u canot be"
OMG WTF I AM SO SERIOS whine whine
af Occupant Ilied Industries 2. maj 2005