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1.
IOI
An Indicator of Interest. Jargon used by a PUA. When he is talking to a girl, she will IOI him with subtle things, a trained eye can pick these up easily.

After three IOIs it is possible to go in for the kiss
Examples of IOIs:
1. If she starts playing with her hair
2. If she laughs at things that are not funny (being giggly)
3. If she asks you her name
4. You squeaze her hand, she squeazes back.
af Kurent 12. august 2006
 
2.
A common short form for "indicators of interest", which is a phrase commonly found on forums for dating advice. Mostly describing the behaviour of women when noticing guys (at a club/bar)

- At a club, guys go after the girls who show IOI's.
When scouting a party for chicks, go after the ones who show IOIs
af Gandolf Randolf 9. august 2006
 
3.
IOI
I'm Over It
Yvette: Hey did you hear about Lisa going postal over a comment I left on fb?
Gloria: IOI...she's bat shit crazy and will never change...
af Gloria Alcatraz 18. juni 2012
 
4.
ioi
an acronym for the words "I'm Over It". not to be confused with the term "lol". they may look alike, but soon enough everyone will be using ioi more.
That bitch just made out with my ex! Oh whatever, ioi. He was a bad kisser anyway.
af 36scores 20. juni 2011
 
5.
ioi
variation of 'lol'. true hackers use the word: ioi instead of lol. capital i's look like L's
<seicher> uh i like but sex
<pat_> ioi@u
af pat_ 22. februar 2003