Top Definition
When a woman in on her period (aka "up on blocks"). Similar to "lockdown"
We can't have sex this weekend because my girlfriend is on blockdown.
af Anthony Gentile 30. april 2007
1 more definition
When you block someone on your friends list.
Friend #1: "I'm tired of Joe posting sarcastic messages on my status updates."
Friend #2: "Girl! You need to put him on BlockDown!"
af Lolita75 16. januar 2010

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